In pharmaceutical and life science research, small mistakes can go beyond simple operational errors, leading to reduced reproducibility, data inaccuracies, regulatory delays, or even production losses.
However, such human errors often arise not merely from individual mistakes but from the inherently complex and repetitive nature of manual workflows. Recently, reports from other industries have shown that adopting automation systems significantly reduces human error, drawing growing interest in the pharmaceutical and life science sectors regarding the need for and benefits of automation.
Data-Based Case: The Effect of NGS Prep Automation
In real laboratory settings, even when using the same conditions and reagents, manual pipetting often results in variations between experiments. In workflows like NGS Prep, where precise dispensing is critical, these variations can accumulate, affecting library quality and sequencing outcomes.
The image below compares results under identical conditions using the same enzyme and buffer lot: manual dispensing versus automated dispensing with NOTABLE.
*Quality Analysis with Company A TapeStation
๐ฌ Key Observed Differences
The manual dispensing group (left) showed an average concentration of 1399 ng with a standard deviation of ยฑ123.5. By contrast, the automated group achieved an average of 1541 ng with a standard deviation of ยฑ65.8โcutting the variance nearly in half. The automated group also displayed consistent distribution across all samples, with clear target bands (approx. 300โ400 bp) visible in every sample.
This demonstrates that automated liquid handling goes beyond replacing repetitive tasks; it is a practical way to minimize sample-to-sample differences and secure reproducibility in experiments.
Laboratory automation reduces dependence on operator skill level, ensuring that repetitive tasks prone to error are carried out reliably. In workflows involving numerous stepsโsuch as precise reagent dispensing, dilution, mixing, or plate-to-plate sample transfersโthe benefits of automation in precision, consistency, and time savings become especially evident.
โ
Reduce variation and enhance workflow stability with NOTABLE.
At ABLE Labs, we address these laboratory challenges by offering automation solutions powered by liquid handling robots. Automation is more than reducing manual repetitionโit enables a level of precision and reproducibility beyond human control,ย standardizing experimental quality that would otherwise vary based on operator experience.
๐๏ธ Watch ABLE Labsโ Lab Automation in Action
In pharmaceutical and life science research, small mistakes can go beyond simple operational errors, leading to reduced reproducibility, data inaccuracies, regulatory delays, or even production losses.
However, such human errors often arise not merely from individual mistakes but from the inherently complex and repetitive nature of manual workflows. Recently, reports from other industries have shown that adopting automation systems significantly reduces human error, drawing growing interest in the pharmaceutical and life science sectors regarding the need for and benefits of automation.
Data-Based Case: The Effect of NGS Prep Automation
In real laboratory settings, even when using the same conditions and reagents, manual pipetting often results in variations between experiments. In workflows like NGS Prep, where precise dispensing is critical, these variations can accumulate, affecting library quality and sequencing outcomes.
The image below compares results under identical conditions using the same enzyme and buffer lot: manual dispensing versus automated dispensing with NOTABLE.
Left three samples (B1โD1): Manual dispensing
Right six samples (E1โB2): Automated dispensing using NOTABLE
๐ฌ Key Observed Differences
Manual dispensing group average concentration: 1399 ยฑ 123.5 ng
Automated dispensing group average concentration: 1541 ยฑ 65.8 ng
The manual dispensing group (left) showed an average concentration of 1399 ng with a standard deviation of ยฑ123.5. By contrast, the automated group achieved an average of 1541 ng with a standard deviation of ยฑ65.8โcutting the variance nearly in half. The automated group also displayed consistent distribution across all samples, with clear target bands (approx. 300โ400 bp) visible in every sample.
This demonstrates that automated liquid handling goes beyond replacing repetitive tasks; it is a practical way to minimize sample-to-sample differences and secure reproducibility in experiments.
Laboratory automation reduces dependence on operator skill level, ensuring that repetitive tasks prone to error are carried out reliably. In workflows involving numerous stepsโsuch as precise reagent dispensing, dilution, mixing, or plate-to-plate sample transfersโthe benefits of automation in precision, consistency, and time savings become especially evident.
โ Reduce variation and enhance workflow stability with NOTABLE.
At ABLE Labs, we address these laboratory challenges by offering automation solutions powered by liquid handling robots. Automation is more than reducing manual repetitionโit enables a level of precision and reproducibility beyond human control,ย standardizing experimental quality that would otherwise vary based on operator experience.
๐๏ธ Watch ABLE Labsโ Lab Automation in Action