NEWSLETTERCan Repeated Experimental Errors Be Reduced with Lab Automation?

In pharmaceutical and life science research, small mistakes can go beyond simple operational errors, leading to reduced reproducibility, data inaccuracies, regulatory delays, or even production losses.


However, such human errors often arise not merely from individual mistakes but from the inherently complex and repetitive nature of manual workflows. Recently, reports from other industries have shown that adopting automation systems significantly reduces human error, drawing growing interest in the pharmaceutical and life science sectors regarding the need for and benefits of automation.



Data-Based Case: The Effect of NGS Prep Automation

In real laboratory settings, even when using the same conditions and reagents, manual pipetting often results in variations between experiments. In workflows like NGS Prep, where precise dispensing is critical, these variations can accumulate, affecting library quality and sequencing outcomes.

The image below compares results under identical conditions using the same enzyme and buffer lot: manual dispensing versus automated dispensing with NOTABLE.


*Quality Analysis with Company A TapeStation


  • Left three samples (B1–D1): Manual dispensing

  • Right six samples (E1–B2): Automated dispensing using NOTABLE


๐Ÿ”ฌ Key Observed Differences

  • Manual dispensing group average concentration: 1399 ± 123.5 ng

  • Automated dispensing group average concentration: 1541 ± 65.8 ng


The manual dispensing group (left) showed an average concentration of 1399 ng with a standard deviation of ±123.5. By contrast, the automated group achieved an average of 1541 ng with a standard deviation of ±65.8—cutting the variance nearly in half. The automated group also displayed consistent distribution across all samples, with clear target bands (approx. 300–400 bp) visible in every sample.

This demonstrates that automated liquid handling goes beyond replacing repetitive tasks; it is a practical way to minimize sample-to-sample differences and secure reproducibility in experiments.



Laboratory automation reduces dependence on operator skill level, ensuring that repetitive tasks prone to error are carried out reliably. In workflows involving numerous steps—such as precise reagent dispensing, dilution, mixing, or plate-to-plate sample transfers—the benefits of automation in precision, consistency, and time savings become especially evident.



โœ… Reduce variation and enhance workflow stability with NOTABLE.

At ABLE Labs, we address these laboratory challenges by offering automation solutions powered by liquid handling robots. Automation is more than reducing manual repetition—it enables a level of precision and reproducibility beyond human control, standardizing experimental quality that would otherwise vary based on operator experience.



๐ŸŽž๏ธ Watch ABLE Labs’ Lab Automation in Action

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Copyright โ’ธ 2024 ABLE Labs Inc. ใ…ฃ ABLE Labs ใ…ฃ12th fl., 13-39, Songdogwahak-ro 16 beon-gil, Yeonsu-gu, Incheon, Republic of Korea ใ…ฃ info@ablelabsinc.com ใ…ฃ 032-202-3555